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CHIP-Seq Protein-DNA Interaction

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Home > NGS Library Construction > DNA Sequencing > CHIP-Seq Protein-DNA Interaction
DNA Sequencing
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CHIP-Seq Protein-DNA Interaction

Clontech

Protein-DNA interaction analysis of a genome using chromatin immunoprecipitation sequencing

CHIP-Seq Protein-DNA Interaction
Clontech

Chromatin immunoprecipitation sequencing (ChIP-seq) has facilitated tremendous progress for epigenetics research. Given that many proteins of interest (e.g. transcription factors and modified histones) are associated with a limited number of specific genomic loci, the amount of DNA recovered by chromatin immunoprecipitation can be quite low, posing challenges for the generation of representative ChIP-seq libraries.

 

You can choose from available kits

SMARTer ThruPLEX DNA-seq Kit

  • Illumina library construction
  • Inputs of 50 pg – 50 ng double-stranded ChIP DNA
  • Directly compatible with the DNA SMART ChIP-Seq Kit

 

DNA SMART ChIP-Seq Kit

  • Highly sensitive kit generates robust sequencing libraries from low-input DNA samples
  • Inputs of 100 pg – 10 ng of single or double-stranded DNA
  • Ligation-free protocol
  • Illumina-ready sequencing libraries
  • Multiplexing of up to 48 samples
  • Generates libraries in 4 hours

 

ChIP Elute Kit

  • Fast (one hour) cross-link reversal and elution of ChIP DNA
  • Replaces long and tedious protocols for the final stages of ChIP experiments
  • ssDNA can be recovered in one hour compared to traditional methods that may require overnight incubation
  • Directly compatible with the DNA SMART ChIP-Seq Kit

 

Documents and resources

For more information visit producer's website.

SELECTION GUIDE Next-Gen Sequencing Kits 

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