Single-Cell Whole Genome Amplification

Clontech

The SMARTer PicoPLEX Kits with patented technology is designed and optimized for amplification of single-copy genomic DNA starting with a single cell. The easy-to-use single-tube protocol reduces handling errors, dramatically improves time to results, and reduces background.  PicoPLEX WGA has long been used by IVF clinics worldwide for pre-implantation genetic screening and diagnosis in detecting chromosomal aneuploidies and copy number variations (CNV).

• Compatible with single-cell or ultra-low inputs
• Reproducible, informative results with low sequence coverage
• Ligation-free protocol
• Solutions for both NGS and PCR/array-based approaches
• Three-step, single-tube protocol takes less than 3 hours

 

You can choose from available kits

SMARTer PicoPLEX DNA-seq Kit

• Illumina library construction
• Inputs of 1-10 mammalian cells or 6-60 pg gDNA
• Library quantification not required
• Illumina-ready sequencing libraries
• Multiplexing of up to 48 samples
• A single kit contains everything needed to prepare a sequencing-ready library

 

SMARTer PicoPLEX WGA Kit

• PCR/array-based analysis
• Inputs of 1-10 mammalian cells or 6-60 pg gDNA
• Superior reproducibility of allele representation
• Easy to use and automate

 

Documents and resources

For more information about PicoPLEX DNA-seq Kit visit producer's website.

For more information about PicoPLEX WGA Kit visit producer's website.

Downlands SELECTION GUIDE Next-Gen Sequencing Kits